2012年获同济大学临床医学系学士学位

2015年获同济大学临床医学系博士学位

2012.12-2014.01，美国得克萨斯州立大学贾维斯顿医学分部，访问学者

2015.08-2018.06，电子科技大学附属医院·四川省人民医院，医师

2018.04至今，电子科技大学附属医院·四川省人民医院，主治医师

2022.11至今，电子科技大学附属医院·四川省人民医院，副研究员

主要从事肠黏膜免疫以及神经免疫病理机制研究。四川省“天府青城计划”科技菁英、电子科技大学“百人计划”、四川省杰出青年科技人才；主持国家自然科学基金面上项目2项、青年项目1项，主持包括四川省科技厅四川省自然科学基金重点项目、四川省科技计划项目、电子科技大学面向重大需求类项目、四川省人社厅留学归国人员择优资助项目在内等多项课题；作为研究骨干参与国家科技部重点研发计划、国家自然科学基金区域创新联合基金重点项目、四川省科技厅重点研发项目和青年科技创新研究团队等省部级课题多项；以第一作者或通讯作者身份在Science Translational Medicine, Gastroenterology, Gut, Mucosal  Immunol, J Immunol, J Innate Immun等杂志发表SCI论文数十篇。

近5年主持科研项目：

1) 炎症性肠病小脑损伤的特征及机制研究(国家自然科学基金-面上项目)

2) Steap2调控炎症性肠病肠黏膜炎症及伴发视网膜损伤的机制研究(四川省科技厅-四川省自然科学基金-重点项目)

3)鼠尾草酚调控IBD肠黏膜T细胞免疫应答及肠外神经损伤的机制研究(四川省科技厅杰出青年科技人才项目）

4)肠源性效应辅助性T细胞调节炎症性肠病视网膜损伤的机制研究（国家自然科学基金面上项目）

代表性论著:

1) He C*#, Xiu W#, Chen Q#, Peng K#, Zhu X, Wang Z, Xu X, Chen Y,  Zhang G, Fu J, Dong Q, Wu X, Li A, Liu D, Gao Y, Wang J, Wang Z, Deng B,  Shuai P, Gao C, Chen Y, Yu L, Lu F*. Gut-licensed β7+ CD4+  T cells contribute to progressive retinal ganglion cell damage in glaucoma. Sci  Transl Med. 2023 Aug 2;15(707):eadg1656. 共同通讯作者IF:17.96 中科院医学1区

2) Chong He#, Tianming Yu#, Yan Shi, Caiyun Ma, Wenjing Yang, Leilei  Fang,  Mingming Sun, Wei Wu, Fei Xiao,  Feifan Guo, Minhu Chen, Hong Yang, Jiaming   Qian, Yingzi Cong*, Zhanju Liu*, MicroRNA301A Promotes Intestinal  Inflammation and Colitis-Associated Cancer  Development by Inhibiting BTG1. Gastroenterology (2017),152(6),1434-1448.e15.  IF: 19.233 中科院医学1区

3) Chong  He#, Yan Shi#, Ruijin  Wu#,  Mingming Sun, Leilei Fang, Wei  Wu, Changqin Liu, Maochun Tang, Zhong Li, Ping  Wang, Yingzi Cong, Zhanju Liu*, miR-301a  promotes intestinal mucosal inflammation   through induction of IL-17A and TNF-a in IBD. Gut (2016), 65  (12), 1938-1950. IF: 17.943 中科院医学1区

4) Wei  Wu#, Chong He#,  Changqin Liu, Anthony T  Cao, Xiaochang  Xue, Heather L Evans-Marin, Mingming Sun, Leilei Fang, Suxia  Yao, Irina V Pinchuk, Don W Powell, Zhanju  Liu*, Yingzi Cong*, miR-10a  inhibits  dendritic cell activation and Th1/Th17 cell immune responses in IBD.  Gut (2015), 64 (11), 1755-64. 共同第一作者IF: 17.943 中科院医学1区

5) He C, Peng K, Zhu X, Wang Z, Xiu W, Zhang G, Chen Y, Sun C, Xiao X, Liu D, Li A, Gao Y, Wang J, Shuai P, Chen Y, Yu L, Lu F. Th1 cells contribute to retinal ganglion cell loss in glaucoma in a VCAM-1-dependent manner. J Neuroinflammation. 2024 Feb 5;21(1):43. 中科院医学1区

6) Yan  Shi#, Chong He#,  Caiyun Ma, Tianming Yu,  Yingzi Cong,  Wei Cai*, Zhanju Liu*. Smad nuclear interacting protein 1  (SNIP1) inhibits intestinal inflammation  through regulation of epithelial   barrier function. Mucosal Immunol (2018), 11 (3), 835-845共同第一作者IF: 7.352 中科院医学1区

7) Mingming  Sun#, Chong  He#, Yingzi Cong* and Zhanju  Liu*.  Regulatory immune cells in regulation of intestinal inflammatory  response to microbiota. Mucosal Immunol  (2015), 8 (5), 969-978共同第一作者IF: 7.352 中科院医学1区

8) Huang X#, Pan Y#, Liu Y#, Zhou Z, Zhang Y, Gao C, He C*.  Clinical Utility of the Neutrophil-to-Bilirubin Ratio in the Detection of  Disease Activity in Ulcerative Colitis. J Inflamm Res. 2023 Jun  16;16:2549-2559.通讯作者IF:4.631

9) Huang Xijing, Ya Liu, Zhou Zhou, Yan Pan, Yinghui Zhang,  Caiping Gao, Chong He. Clinical significance of the C-reactive  protein-to-bilirubin ratio in patients with ulcerative colitis. Front Med  (Lausanne).2023. 通讯作者IF:5.093

10) Zhou Z#, Zhang Y#, Pan Y, Yang X, Li L, Gao C*, He C*.  A Novel Neutrophil-Based Biomarker to Monitor Disease Activity and Predict  Response to Infliximab Therapy in Patients With Ulcerative Colitis. Front Med  (Lausanne).2022 Apr 27;9:872831. 通讯作者IF:5.093

11) Zhou Z, Zhang Y, Yang X,  Pan Y, Li L, Gao C*, He C. Clinical Significance of Novel  Neutrophil-Based Biomarkers in the Diagnosis and Prediction of Response to  Infliximab Therapy in Crohn's Disease. Front Immunol. 2022 Mar 4;13:865968. 通讯作者IF:7.561

12) Xu X#, Zhang G#, Peng K,  Gao Y, Wang J, Gao C, He C*, Lu F*. Carnosol Maintains Intestinal  Barrier Function and Mucosal Immune Homeostasis in DSS-Induced Colitis. Front  Nutr. 2022 May 24;9:894307. 共同通讯作者IF:6.58

13) He C*#, Zhang G#, Fu J, Zhang  R, Li A, Liu D, Li B, Chen Y, Deng B, Chen Y, Shuai P, Lu F*. Clinical  Significance of Albumin- and Bilirubin-Based Biomarkers in Glaucoma: A  Retrospective Case-Control Study. Oxid Med Cell Longev. 2022 Mar  4;2022:8063651. 共同通讯作者IF:6.54

14) Peng K, Xiao J, Wang J,  Song Y, Wu L, Xiu W, Chen Q, Chen Y, Shuai P, He C*, Lu F*. MAdCAM-1  mediates retinal neuron degeneration in experimental colitis through  recruiting gut-homing CD4+ T cells. Mucosal Immunol. 2021 Jan;14(1):152-163. 共同通讯作者IF: 7.352

15) Mingming Sun#, Chong He#,  Liang Chen#, Wenjing Yang, Wei Wu, Feidi  Chen, Anthony T. Cao,  Suxia Yao, Sara  M. Dann, T. G. Murali Dhar, Luisa Salter-Cid, Qihong Zhao,  Zhanju Liu and Yingzi Cong. RORγt Represses IL-10  Production in Th17  Cells To Maintain  Their Pathogenicity in Inducing Intestinal Inflammation. J  Immunol (2019),202(1),79-92. 共同第一作者IF: 4.718

16) Wei Wu#, Yang Song#,Chong  He#, Changqin Liu, Ruijin Wu, Yingzi Cong*, ZhanjuLiu*. Divalent  metal-ion transporter 1 is decreased in intestinal epithelialcells and  contributes to the anemia in inflammatory bowel disease. Sci Rep(2015), 5,  16344共同第一作者IF: 4.011

入选四川省“天府青城计划”、电子科技大学“百人计划”、四川省杰出青年科技人才