2015年获重庆医科大学临床医学学士学位

2018年获上海交通大学内科学硕士学位

2022年获香港大学生物医学博士学位

2022年-2024年在上海交通大学医学院附属仁济医院消化疾病研究所从事博士后研究工作

2024年在四川省人民医院消化内科工作至今

作为项目负责人主持国家自然科学基金2项（面上项目：产雌马酚阿德氏菌调控中性粒细胞O-GlcNAc糖基化修饰增强结直肠癌免疫治疗疗效的机制研究；青年项目： TMAO上调逆转座子LINE-1介导精氨酸代谢激活进而促进大肠癌进展的机制研究），以及四川省科技厅项目1项，上海市科委扬帆人才专项1项。以第一或通讯作者身份在《Cell Metabolism》、《Cell Host & Microbe》、《Cell Reports》等国际期刊上发表学术论文17篇，其中SCI论文17篇，累积影响因子176分。

以第一作者或通讯作者（含共同）发表的主要学术论文：

1、 Muni Hu#, Xiaoqiang Zhu#, et al. Optimizing anti-PD-1/PD-L1 therapy efficacy and fecal microbiota transplantation donor selection through gut mycobiome-based enterotype. Cell Reports. 2025 Apr 20;44(5):115589.

2、Xiaoqiang Zhu#, et al.Interplay Between Gut Microbial Communities and Metabolites modulates Pan-Cancer Immunotherapy Responses. Cell Metabolism.

3、Xiaoqiang Zhu#, et al. A specific enterotype derived from gut microbiome of older individuals enables favorable responses to immune checkpoint blockade therapy. Cell Host Microbe. 2024 Mar 18: S1931-3128(24)00075-1.

4、Ze Zhang#, Xiaoqiang Zhu#, et al. Single-cell mapping reveals several immune subsets associated with liver metastasis of pancreatic ductal adenocarcinoma. Med. 2023 Oct 13;4(10):728-743.e7.

5、Chenhao Zhou#, et al, Xiaoqiang Zhu*, Ning Ren*. Whole-exome sequencing reveals the metastatic potential of hepatocellular carcinoma from the perspective of tumor and circulating tumor DNA. Hepatol Int. 2023 May 23. 17(6):1461-1476.

6、Xiaoqiang Zhu, et al. Overexpression of transposable elements is associated with immune evasion and poor outcome in colorectal cancer. Eur J Cancer. 2021 Sep 4; 157: 94-107.

7、Xiaoqiang Zhu, et al. A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients. NPJ Precis Oncol. 2021 Feb 12;5(1):7.

8、Xiaoqiang Zhu, et al. A long non-coding RNA signature to improve prognosis prediction

of gastric cancer. Mol Cancer. 2016 Sep 20; 15(1):60.

9、Qian Liang#, Dan Ma#, Xiaoqiang Zhu#, et al. RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer. Clin Cancer Res. 2018 Mar 15;24(6):1473-1485.

10、Xiaoqiang Zhu et al. GeneExpressScore Signature: a robust prognostic and predictive classifier in gastric cancer. Mol Oncol. 2018 Nov;12 (11):1871-1883.

2022年获全国博士后国（境）外交流项目